Evidence before closure.

Scientific implementation baseline is Biomarker Matrix v1.1 and remains non-diagnostic.

Method: automated · critical

Evidence: Biomarker Matrix v1.1 is recorded as the reviewed implementation baseline in docs/SCIENTIFIC_GOVERNANCE.md and docs/SCIENTIFIC_BASELINE_V1_1.md.

Same P17 scenario and seed reproduce the same fingerprint without silent imputation.

Method: automated · critical

Evidence: P17 deterministic replay and no-imputation tests pass in the repository test suite.

Critical story can be followed from live monitoring through explainability, guidance, offline mode and ground sync without broken navigation.

Method: manual browser · critical

Evidence: Browser walkthrough (headless Chromium 1280x1800, local dev origin) of the Mission Day 127 critical story: / -> /mission/live -> /mission/readiness -> /mission/intelligence -> /mission/guidance -> /mission/offline -> /mission/ground -> /mission/simulation -> /mission/validation. Every route rendered with its own title, exactly one <main> and one <h1>, zero console/page errors and zero horizontal overflow. Mission -> Mission Scenario resolved to /mission/simulation and About -> Validation & Limitations navigated to /mission/validation (title 'Validation & Usability | The Mitochondria'). No broken navigation observed.

All critical routes, menus, controls and dialogs are reachable and operable by keyboard with visible focus.

Method: manual browser · critical

Evidence: Keyboard-only review on / and /mission/live. Tab order reached logo, skip/section links, all six top-level menu triggers, the external NASA link and hero actions; on /mission/live it reached Readiness, Public site, Connect BLE heart rate, the self-check select, the note input and Record check-in. Focus is visible via :focus-visible (document.activeElement.matches(':focus-visible') true; ring box-shadow oklch(0.79 0.145 206) 1px). Menus open with Enter, move with ArrowDown to role=menuitem, and close with Escape. The self-check select opened with Enter, changed value by ArrowDown+Enter ('Monitor / not at best'), and Record check-in activated with Enter, producing the 'Last recorded at' confirmation. No keyboard trap and no hover-only control encountered.

Critical routes remain usable on narrow/touch layouts without horizontal overflow or inaccessible controls.

Method: manual browser · critical

Evidence: Responsive/touch review at 390x844 with touch and mobile emulation. All nine critical routes reported 0px horizontal overflow and no page errors. The mobile navigation opened by tap into a role=dialog panel and body overflow became 'hidden' (scroll lock). Primary buttons and menu rows met touch sizing. Observation, not a blocker: inline footer/menu text links render about 20px tall, below a 24px box, and are documented for future refinement rather than claimed as fully compliant.

The required P11 daily demo assessment remains below three minutes.

Method: automated · critical

Evidence: P11 automated test verifies the required daily demo assessment completes in under 180 seconds.

Browser validation records sample-to-visible-update timing for the local live path; no cloud round-trip is required.

Method: manual browser · critical

Evidence: Measured local sample-to-visible-update latency on /mission/live using the local self-check capture path (no backend call). Five consecutive runs from user action to the visible confirmation/timeline update: 148.23, 97.76, 116.30, 86.53, 84.55 ms (median 97.76 ms, max 148.23 ms). Network capture during the measurement recorded zero requests to the backend origin or /api/, confirming the visible update requires no cloud round-trip. Latency was measured against locally captured/synthetic input only; target-hardware wearable timing is not included.

Measure software/device battery impact on target wearable hardware when hardware is available.

Method: hardware · noncritical

Evidence: Target-hardware battery drain cannot be truthfully measured without selected wearable hardware; limitation is documented for final evidence collection.

Encrypted local capture survives transport failure and later synchronizes idempotently.

Method: automated · critical

Evidence: P14 encrypted offline queue/reconnect tests and P15 authenticated transport gates pass.

Ground/research authorization and de-identification gates remain enforced.

Method: automated · critical

Evidence: P15/P16 role-separation, RLS and research export security gates pass.

Artifact/dropout scenarios never silently fill safety-relevant values.

Method: automated · critical

Evidence: P17 artifact/dropout tests preserve poor/missing quality states without silent imputation.