P26 · Integrated Astronaut Health Domains

Cardiovascular Health — Measurements & Reference

Heart rate, blood pressure and hydration/posture context; observational only.

The owner reports Nikolas completed verbal scientific review. Formal signed per-entry reconciliation is not recorded. Existing evidence is displayed without clinical inference or approval.

Cardiovascular scientific handbook · research reference

Nikolas' cardiovascular handbook: 96 catalogued measurements across 7 groups, shown in English. The original Greek handbook is preserved unchanged. The owner reports Nikolas completed verbal scientific review; formal signed per-entry reconciliation and translation review are not recorded. No clinical validation, approval, thresholds, diagnoses or alerts are enabled by this reference.

Explore the source-derived measurement catalog

Hemodynamics

  • HR · bpm — Sinoatrial (sinus node) rate and autonomic regulationHR↑ may compensate for SV↓ or reflect exercise; HR↓ may be physiological at rest. Related: Association with BP, SV, posture, ECG

    Review note: Source term for 'sinus node rhythm/rate' rendered as 'sinoatrial (sinus node) rate'; confirm intended terminology.

  • Resting HR · bpm — Baseline heart rate under standardized restThe trend is more important than a single value. Related: Comparable time of day/posture
  • Exercise HR · bpm — Response to workload/O₂ consumptionInterpret relative to workload. Related: VO₂peak, workload
  • HR recovery · bpm difference — Recovery after exertion and autonomic functionSlow recovery is non-specific. Related: Exertion protocol
  • SBP · mmHg — Pressure during systoleA low value on standing may accompany reduced preload. Related: HR, symptoms, posture
  • DBP · mmHg — Pressure during diastoleInfluenced by vascular tone. Related: SBP, MAP
  • MAP · mmHg — Approximate mean perfusion pressureMAP≈DBP+(SBP−DBP)/3 under appropriate conditions. Related: Mark as estimated
  • Pulse pressure · mmHg — SBP−DBP; influenced by SV and arterial elasticityNot an exclusive index of arterial stiffness. Related: BP, PWV

    Review note: Source term 'elasticity' rendered as 'arterial elasticity'; source does not specify arterial vs. general compliance.

  • Stroke volume · mL/beat — Volume of blood ejected per contractionMay decrease with low preload. Related: CO, HR, echo
  • Cardiac output · L/min — Total output = HR×SV/1000May be maintained by HR↑ despite SV↓. Related: HR, SV
  • Cardiac index · L/min/m² — CO adjusted for body surface areaDepends on a correct BSA. Related: CO, BSA
  • SVR · dyn·s/cm⁵ — Resistance of the systemic circulationInfluenced by vascular tone and flow. Related: MAP, CVP, CO
  • CVP · mmHg — Pressure near the right atriumA change in 0 g should not be simplistically interpreted as venous congestion. Related: Posture, intrathoracic pressure
  • Plasma volume · mL / % change — Liquid component of bloodA decrease may limit preload. Related: Hct, hydration, posture
  • Blood volum · mL — Total circulating volumeImportant for orthostasis. Related: Plasma volume, RBC mass

    Review note: Source marker name reads 'Blood volum' (likely 'Blood volume'); name preserved as in source pending review.

  • Venous return · L/min — Blood flow toward the right heartIn steady state it approximates CO. Related: CVP, SV
  • LV EDV · mL — Left ventricular end-diastolic volumeIndex of filling; depends on loading conditions. Related: SV, EF
  • LV ESV · mL — End-systolic volumeRelated to ejection/loading. Related: EDV, EF
  • LV mass · g — Myocardial massChanges may reflect remodeling. Related: Echo method
  • RV function · method-dependent — Right ventricular functionNot replaced by LVEF. Related: Echo protocol
  • LVEF · % — (EDV−ESV)/EDV×100A normal EF does not exclude every form of cardiac dysfunction. Related: LV volumes
  • E/A · ratio — Doppler early/late diastolic fillingInfluenced by age and loading. Related: E/e′, echo
  • E/e′ · ratio — Estimate of filling pressures, with limitationsNot an absolute pressure measurement. Related: Echo quality

Electrical

  • ECG · waveform — Recording of cardiac electrical potentialsRequired to document rhythm. Related: Signal/lead/time
  • RR interval · ms — Interval between successive R wavesBasis of HR and HRV. Related: Artefact rejection
  • SDNN · ms — Standard deviation of NN intervalsDepends on recording duration. Related: 5 min vs 24 h
  • RMSSD · ms — Short-term NN variabilityInfluenced by breathing/artefacts. Related: Rest/posture
  • HF HRV · ms² or normalized — Spectral component of HRVInfluenced by breathing. Related: Breathing rate
  • LF HRV · ms² or normalized — Spectral component of HRVNot equivalent to pure sympathetic activity. Related: Recording conditions
  • PR · ms — Atrioventricular conductionChanges require clinical interpretation. Related: ECG
  • QRS · ms — Ventricular depolarizationWidth depends on conduction. Related: ECG
  • QTc · ms — QT corrected for HRThe correction depends on the formula and HR. Related: Formula, drugs, electrolytes
  • PAC burden · % or /day — Premature atrial contractionsA single PAC is not sufficient for diagnosis. Related: ECG duration
  • PVC burden · % or /day — Premature ventricular contractionsInterpret by burden/symptoms. Related: ECG duration
  • AF burden · % time — Time spent in atrial fibrillationRequires ECG confirmation. Related: ECG annotation
  • SVT/VT episode · event — Tachyarrhythmia episodeMust be flagged by a physician or a validated algorithm. Related: ECG
  • ST changes · mm — ST-segment changesNon-specific without clinical context. Related: ECG leads, symptoms

Orthostatic and autonomic

  • Orthostatic ΔSBP · mmHg — Change in pressure during stand/tiltA drop accompanied by symptoms increases concern. Related: Protocol/time
  • Orthostatic ΔHR · bpm — Compensatory HR responseInterpret together with BP and volume. Related: Protocol/time
  • Tilt tolerance · min/event — Tolerance time during controlled tiltThe protocol affects comparability. Related: Symptoms
  • Baroreflex sensitivity · ms/mmHg — Change in RR per change in pressureDepends on the estimation method. Related: ECG/BP
  • Cerebral flow velocity · cm/s — Doppler cerebral blood flow velocityNot directly equivalent to total cerebral perfusion. Related: Arterial diameter
  • Orthostatic symptoms · categorical — Dizziness/nausea/presyncopeMust be time-synchronized with measurements. Related: BP, HR

Vascular

  • cIMT · mm — Carotid intima-media thicknessDoes not by itself prove coronary artery disease. Related: Age, method
  • PWV · m/s — Pressure-wave velocity/stiffnessA higher value is often associated with stiffness. Related: BP, segment
  • FMD · % — Endothelium-dependent vasodilationHighly protocol-dependent. Related: Baseline diameter
  • Carotid distensibility · %/mmHg — Change in diameter per pressureDepends on BP and image quality. Related: PWV

    Review note: Source term 'image' rendered as 'image quality'; source may mean the imaging itself.

  • CAC score · Agatston — Imaging burden of coronary calciumA CAC of zero does not exclude non-calcified plaque. Related: CT, age
  • Coronary CTA findings · categorical — Plaques/stenoses on CTSpecialized imaging, not a wearable. Related: Radiology
  • Arterial plaque burden · method-specific — Estimate of plaque extentNot equivalent to cIMT. Related: Imaging modality

Venous and coagulation

  • IJV flow direction · forward/stagnant/reverse — Outflow path from the craniumReversed/stagnant flow does not prove a thrombus. Related: Side, posture
  • IJV peak velocity · cm/s — Doppler peak velocityA lower velocity may accompany stasis. Related: Side, angle
  • IJV flow grade · 1–4 — Categorization of venous flowGrade 3 stagnant, grade 4 predominantly reversed. Related: NASA VTE definitions
  • IJV compressibility · yes/no — Ultrasound compressibilityReduced compressibility may support thrombosis. Related: Operator
  • Spontaneous echo contrast · grade — Echogenic phenomenon of slow flowNot a standalone diagnosis of thrombus. Related: Ultrasound
  • Thrombus on ultrasound · yes/no — Visible thrombusRequires specialized clinical confirmation. Related: Location/extent
  • D-dimer · mg/L FEU or DDU — Degradation of stabilized fibrinNon-specific; FEU≠DDU. Related: Assay, clinical context
  • Platelet count · 10⁹/L — Platelet countDoes not by itself describe coagulation. Related: CBC
  • Fibrinogen · g/L — Substrate for fibrin formationAlso increases with inflammation. Related: CRP
  • PT/INR · s/INR — Extrinsic coagulation pathway/anticoagulantsDoes not by itself predict VTE. Related: Medication
  • aPTT · s — Intrinsic coagulation pathwayNot a standalone thrombosis test. Related: Medication
  • vWF · assay — Endothelial/hemostatic systemNon-specific research marker. Related: Assay

Exercise and oxygenation

  • VO₂peak · mL/kg/min — Maximum measured O₂ uptakeA decrease may indicate deconditioning. Related: Protocol, effort
  • Workload · W — Mechanical power during exerciseMust accompany HR/VO₂. Related: Device
  • SpO₂ · % — Peripheral Hb saturationErrors from motion/perfusion. Related: Signal quality
  • PaO₂ · mmHg — Partial pressure of O₂ in arterial bloodRequires a blood sample. Related: Blood gas
  • Respiratory rate · /min — Breathing rateAn increase is non-specific. Related: Activity
  • EtCO₂ · mmHg — End-tidal CO₂Depends on ventilation and sampling. Related: Sensor
  • Lactate · mmol/L — Metabolic state/effortNot specific for cardiac ischemia. Related: Workload

Biochemistry

  • Sodium · mmol/L — Osmotic fluid balanceChanges affect neuromuscular function. Related: Hydration
  • Potassium · mmol/L — Cardiomyocyte membrane potentialExtreme changes are associated with arrhythmias. Related: ECG, renal
  • Magnesium · mmol/L — Electrical stabilityChanges may coexist with rhythm disturbances. Related: K, drugs
  • Calcium serum · mmol/L — Contraction/electrical signalingInfluenced by albumin and pH. Related: Ionized Ca
  • Phosphate · mmol/L — ATP/metabolismInfluenced by kidney, bone and diet. Related: Bone module
  • Hemoglobin · g/dL — Oxygen transportA change in concentration ≠ necessarily a change in RBC mass. Related: Plasma volume
  • Hematocrit · % — Red-cell volume fractionInfluenced by plasma volume. Related: Hb
  • Renin · assay-specific — RAAS and blood pressureDepends on posture, Na and medications. Related: Aldosterone
  • Aldosterone · assay-specific — Na retention/K excretionDepends on posture/time of day. Related: Renin, K
  • Vasopressin/copeptin · assay-specific — Antidiuretic regulationNon-specific under stress. Related: Hydration
  • ANP · pg/mL — Atrial stretch/natriuresisNot equivalent to BNP. Related: Volume
  • BNP/NT-proBNP · pg/mL — Cardiac wall stressInfluenced by kidney function/age. Related: Echo
  • Troponin I/T · assay-specific — Myocardial injuryDoes not by itself prove myocardial infarction. Related: Symptoms/ECG
  • Glucose · mg/dL — Glycemic stateDepends on fasting/stress. Related: Insulin
  • Insulin · μIU/mL — Hormonal glycemic regulationDepends on meal/fasting. Related: Glucose
  • HbA1c · % — Average glycemia over preceding monthsInfluenced by RBC changes. Related: Hb
  • LDL-C · mg/dL — Atherogenic cholesterolChronic risk, not an acute event. Related: ApoB
  • HDL-C · mg/dL — Lipoprotein profileNot a simple inverse causality. Related: Lipids
  • Triglycerides · mg/dL — Metabolic/lipid profileInfluenced by meals. Related: Fasting
  • ApoB · mg/dL — Number of atherogenic particlesComplementary clinical marker. Related: LDL
  • Lp(a) · nmol/L or mg/dL — Inherited atherogenic factorUnits are not directly convertible. Related: Assay
  • hsCRP · mg/L — Systemic inflammationNot specific to the heart. Related: Infection
  • IL-6 · pg/mL — Inflammatory cytokineResearch marker; variable. Related: CRP
  • TNF-α · pg/mL — Inflammatory cytokineNon-specific. Related: Assay
  • 8-OHd · assay-specific — Oxidative DNA damageDoes not diagnose vascular disease. Related: Radiation

    Review note: Source marker name reads '8-OHd' (likely 8-OHdG, 8-hydroxy-2′-deoxyguanosine); name preserved pending review.

  • F2-isoprostanes · assay-specific — Oxidative lipid damageNon-specific. Related: Assay
  • Cortisol · assay-specific — Stress response/circadian rhythmStrong diurnal variation. Related: Sleep/time
Relationship examples (8, research-only)
  • HR↑ + SV↓ + CO≈stable

    Possible compensation for reduced stroke volume through tachycardia; assessment of conditions and method is required.

  • BP↓ standing + dizziness + HR↑

    Compatible with orthostatic intolerance; not a standalone diagnosis. Record the time after standing up.

  • HRV↓ + poor sleep + high workload

    Possible change in autonomic regulation; not a diagnosis of stress or arrhythmia.

  • PWV↑ + BP↑

    Increased blood pressure may affect PWV; do not automatically infer vascular calcification.

  • Normal SpO₂ + Hb↓

    Blood O₂ content may be reduced despite normal saturation.

  • CTX↑ + PWV↑

    Two parallel findings; they do not prove transfer of bone calcium to the vessels.

  • ECG irregular + K⁺ out of range

    Requires verification of ECG quality, electrolyte assessment and clinical review.

    Review note: 'Out of range' references limits that the handbook does not define; no threshold is implied or implemented.

  • Slow venous flow + D-dimer↑

    Increases the need for medical assessment depending on context; does not confirm a thrombus.

Reference-only · pending independent review · not evidence of device availability or independent validation.

Cardiovascular Health measurements · research only

Research-only measurements. No clinical thresholds, diagnosis, readiness score or automatic “OK” assessment. Stored encrypted on this device; not automatically sent to Ground.

The owner reports Nikolas completed verbal scientific review. Formal signed per-entry reconciliation is not recorded; no clinical validation or activation.

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Selected: HR (cv-001)

Handbook and historical units are non-binding, not scientifically approved. No unit conversion.

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Local measurement history

Only records matching the mission and crew IDs above are shown. Different methods or units must not be compared automatically. History is append-only: corrections mark records erroneous and add a superseding entry; nothing is rewritten or deleted.

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Mission-scoped measurements

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Physiological evidence interpretation · research only

The same read-only interpretation used in the Unified Health PDF and TXT. Recorded changes are kept separate from possible biological context; nothing here is a diagnosis or approval.

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Scientific relationship registry

Workload / recovery / autonomic context

Task-linked workload plus sleep/work exposure and recovery signals can identify a coherent workload-recovery pattern.

reviewed non diagnostic · SRC-16, SRC-28

Not evaluated

Hydration / volume / orthostatic context

Hydration and cardiovascular status require corroboration across intake, mass, laboratory/urine and posture-aware signals.

reviewed non diagnostic · SRC-21, SRC-30

Not evaluated

Interpretation boundaries

  • Signals are contextual and not a cardiovascular event detector.
  • Camera PPG is not an arrhythmia diagnostic device; posture and measurement method matter.
  • Evidence presence does not prove a relationship, temporal coincidence, causation or health status.
  • No autonomous diagnosis, alert, treatment or readiness decision.
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